Gene information
Official symbol ABCG2
Official full name ATP binding cassette subfamily G member 2 (Junior blood group)
Gene type protein-coding gene
Chromosome4q22.1
Alias symbolEST157481; MXR; BCRP; ABCP; CD338
Gene familyBlood group antigens; CD molecules; ATP binding cassette subfamily G
Resources
Entrez Gene 9429
HGNC HGNC:74
Ensembl ENSG00000118777
Vega OTTHUMG00000130601
UCSC uc003hrg.4
GO terms: 33 records
GO Description Category LogP Number of genes Detail
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003018 vascular process in circulatory system GO Biological Processes -47.1670528 52 More
GO:0005342 organic acid transmembrane transporter activity GO Molecular Functions -1.32561631 5 More
GO:0006820 anion transport GO Biological Processes -2.9816627 14 More
GO:0006869 lipid transport GO Biological Processes -16.6388990 29 More
GO:0008028 monocarboxylic acid transmembrane transporter activity GO Molecular Functions -1.46322330 3 More
GO:0009636 response to toxic substance GO Biological Processes -18.1818984 46 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0010232 vascular transport GO Biological Processes -6.06441304 9 More
GO:0010876 lipid localization GO Biological Processes -20.1994935 34 More
GO:0015399 primary active transmembrane transporter activity GO Molecular Functions -1.80269149 6 More
GO:0015711 organic anion transport GO Biological Processes -3.37633297 12 More
GO:0015718 monocarboxylic acid transport GO Biological Processes -6.61280961 10 More
GO:0015849 organic acid transport GO Biological Processes -6.14345140 15 More
GO:0016324 apical plasma membrane GO Cellular Components -4.50542891 15 More
GO:0022804 active transmembrane transporter activity GO Molecular Functions -1.58321714 10 More
GO:0031253 cell projection membrane GO Cellular Components -3.08510132 12 More
GO:0031526 brush border membrane GO Cellular Components -3.31231720 5 More
GO:0042626 ATPase-coupled transmembrane transporter activity GO Molecular Functions -2.20105170 5 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0042886 amide transport GO Biological Processes -5.62242821 10 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0045177 apical part of cell GO Cellular Components -8.17813885 46 More
GO:0046942 carboxylic acid transport GO Biological Processes -4.62504459 12 More
GO:0046943 carboxylic acid transmembrane transporter activity GO Molecular Functions -1.33493457 5 More
GO:0097237 cellular response to toxic substance GO Biological Processes -13.7473733 28 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0098754 detoxification GO Biological Processes -12.4136065 17 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:0140352 export from cell GO Biological Processes -8.94733589 48 More
GO:0140359 ABC-type transporter activity GO Molecular Functions -3.54822320 5 More
GO:0150104 transport across blood-brain barrier GO Biological Processes -6.06441304 9 More
GO:1990748 cellular detoxification GO Biological Processes -12.8821364 16 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa02010 ABC transporters KEGG Pathway -3.72474182 5 More
Drug-Gene interaction
view
Related drugs: 62 records
Drug name Interaction type Source PMID View
7-ethyl-10-hydroxycamptothecin PharmGKB view
allopurinol PharmGKB 293412372681013430924126 view
alvocidib NCI 11205902 view
apixaban PharmGKB 2867804929457840 view
atorvastatin PharmGKB 19474787 view
capecitabine PharmGKB 2433821720530282 view
ceftriaxone PharmGKB 29873816 view
chembl428402 DTC 18678495 view
chembl444075 DTC 26197160 view
chembl488910 DTC 243043872226677924611893 view
chlorpromazine NCI 18834354 view
curcumin PharmGKB 25587128 view
cyclophosphamide PharmGKB view
cyclosporine DTCNCIPharmGKB 214886861680596117031644 view
dasatinib PharmGKB 24322003 view
daunorubicin PharmGKB 24021215 view
deferasirox PharmGKB 283460592719399327043265 view
delavirdine DTC 21189339 view
docetaxel PharmGKB 21151855 view
dolutegravir PharmGKB 28858994 view
doxorubicin PharmGKB 11956086 view
efavirenz DTCPharmGKB 2385957121189339 view
elacridar DTCPharmGKB 22266779 view
erlotinib NCI 18723475 view
etravirine DTC 21189339 view
fluorouracil PharmGKB 240187732433821720530282 view
fluvastatin PharmGKB 19842935 view
gefitinib PharmGKB 25554506213323102003542517148776 view
gemcitabine PharmGKB view
genistein NCI 15290869 view
imatinib NCIPharmGKB 241236001580525230713339189810092432200315155841 view
irinotecan PharmGKB 2401877318221820 view
itraconazole NCI 17518356 view
ketoconazole NCI 17518356 view
lamivudine PharmGKB view
lamotrigine PharmGKB 276107472979101426213157 view
leucovorin PharmGKB 240187732433821720530282 view
methotrexate PharmGKB 20386493182372722721705129791011257784681825669221317831 view
mitoxantrone TEND view
nevirapine DTC 21189339 view
nilotinib PharmGKB 24322003 view
nitrofurantoin NCI 17093006 view
oxaliplatin PharmGKB 2433821720530282 view
paclitaxel PharmGKB 21151855 view
pazopanib PharmGKB 25504632 view
prasterone NCI 15448171 view
pravastatin NCIPharmGKB 1984293517622941 view
prazosin DTC 23073734 view
retusin DTC 23851114 view
rosuvastatin PharmGKB 22331829239306751678473620207952206799602563098420130569283229411947478718617601 view
rucaparib PharmGKB view
silybin a NCI 15290869 view
simvastatin PharmGKB 2459871819842935 view
sirolimus NCI 17031644 view
sulfasalazine PharmGKBTTD 25872459243941992832294118167504 view
sunitinib PharmGKB 253444522624457424013576 view
tacrolimus NCI 17031644 view
tariquidar DTC 20621487 view
tenofovir PharmGKB 28462920 view
topotecan PharmGKB 27052877 view
voriconazole NCI 17518356 view
zidovudine PharmGKB 22960662 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_004827.3:c.421C>A genomics rosuvastatin[treatment (pharmacotherapy)] acute myocardial infarction Bailey KM et al. Circ Cardiovasc Genet. 2010
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